Genome-wide approaches for identifying genetic risk factors for osteoporosis
نویسندگان
چکیده
منابع مشابه
Identifying genetic risk factors for osteoporosis.
Over the past decades epidemiological research of so-called "complex" diseases, i.e., common age-related disorders such as cancer, cardiovascular disease, diabetes, and osteoporosis, has identified anthropometric, behavioural, and serum parameters as risk factors. Recently, genetic polymorphisms have gained considerable interest, propelled by the Human Genome Project and its sequela that have i...
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15 صفحه اولEnvironmental risk factors for osteoporosis.
The experiments aimed at evaluating the optimal parameters in the chemo-immunotherapeutic treatment of the L1210 lymphoid leukaemia grafted to [female BALB/c (H2d) x male DBA/2 (H2d)]Fl hybrid mice, hereafter referred to as CDF1 mice. In vitro irradiation of leukaemic ascites cells by X-or y-rays and subsequent inoculation in mice showed that optimum immunogenicity is radiation dose-dependent. ...
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BACKGROUND Colorectal cancer is the second leading cause of cancer-related death, and most colorectal cancer usually arises from colorectal adenomas. Removal of polyps reduces mortality from colorectal cancer. Colorectal adenomas are known to aggregate in families; however, the genetic determinants for risk of polyps are largely unknown. METHODS In this study, we used data from the Tennessee ...
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ژورنال
عنوان ژورنال: Genome Medicine
سال: 2013
ISSN: 1756-994X
DOI: 10.1186/gm448